Clinical Care Toolkit

A better understanding of how the adaptive immune system is regulated has led to the development of novel immunotherapeutic agents and moved immunotherapy to the forefront of cancer treatment. As immunotherapies continue to change treatment paradigms at a rapid pace, it is essential that oncologists and other clinicians are able to effectively incorporate these agents into practice to maximize patient outcomes. The management of immune-related adverse events (irAEs) associated with immunotherapies differs significantly from the side effects of traditional chemotherapy and clinicians must be able to anticipate and treat potential irAEs. In this Clinical Care Toolkit, you will find links and information about immune system regulation, the mechanism of action of immune checkpoint inhibitors, and strategies for managing possible adverse events with these agents. Click on the links below to begin exploring the CATALYST initiative.

Immune System Regulation

Learn about ways in which tumors evade immune system detection and how immune checkpoint inhibitors can unleash the immune system’s ability to fight cancer.

Current and Emerging Immunotherapies

Review results from recent clinical trials on the safety and efficacy of current and emerging immunotherapies.

Managing Adverse Events

Find evidence-based guidance on the management of common immune-related adverse events (irAEs).

Additional Resources

Discover new resources on clinical trials, patient education, treatment guidelines, and more.